Is it safe to drink alcohol while taking Adderall?

Adderall is most commonly used to treat attention-deficient hyperactivity disorder or ADHD. According to research, many people who use Adderall drink alcohol while taking the medication.

A 2013 study found that 46.4 percent of students who used Adderall non-medically had simultaneously used alcohol within the past year.

Another study found that 19 percent of people surveyed, who were prescribed Adderall to treat ADHD, intentionally misused their medication while drinking alcohol.

Although many people do it, mixing alcohol and Adderall can be life-threatening, especially when people consume them at the same time.

Is it safe to drink while taking Adderall?


Drinking alcohol while taking Adderall can be dangerous, as both contain chemicals that affect the central nervous system differently.

Drinking alcohol while taking Adderall can be dangerous. Combining alcohol and Adderall is especially dangerous for people using Adderall for non-medical purposes.

A 2013 report found that 19 percent of the emergency room visits related to ADHD medications in the United States, involving people aged 18 to 25, also involved alcohol use.

Examples of misusing Adderall include:

  • using the medication in a way not prescribed, such as more frequently or in larger doses
  • taking the medication in a different form than prescribed, such as crushing the tablets or opening the pills and smoking, snorting, or injecting the contents
  • taking someone else’s Adderall or using it for non-medical purposes, such as for studying, partying, or getting high

Why is it dangerous?

Adderall and alcohol contain chemicals that affect the central nervous system differently.

Adderall contains chemical salts that increase the effect of the neurotransmitters dopamine and norepinephrine in areas of the brain that improve focus and alertness.

Alcohol decreases the effects of neurotransmitters in the brain, slowing down bodily processes and mental function.

There are a few reasons why mixing alcohol and stimulants, such as Adderall, is not safe.

Alcohol is a depressant in moderate to large quantities. But in small doses, such as a glass of wine or beer, it usually acts as a temporary stimulant. This means Adderall may intensify and lengthen the period of stimulation people experience after a few drinks.

It may also delay the sedating effects of larger doses of alcohol, which might cause people to drink more than they would do otherwise. Consuming large quantities of alcohol can overwhelm the liver, leading to an alcohol overdose.

In other words, Adderall masks the sedating effects of alcohol that usually help prevent people from overdosing on alcohol.

Alcohol and the stimulants in Adderall also require the same liver enzymes for digestion.

People who drink while on Adderall may also feel the effects of one of the two drugs more than usual, depending on which drug is processed quicker by the liver.

Symptoms and side effects

Mixing the two can intensify the effects of Adderall and alcohol in the body.

Adderall and alcohol in moderate-to-large amounts usually cause very different symptoms.

The specific side effects associated with consuming Adderall and alcohol depend on how the two drugs have combined in the body.

Adderall can also cause different symptoms in people who are not using Adderall for medical purposes or not taking it as prescribed.

If someone has a few drinks, they will usually feel a temporary buzz, similar to the rush of euphoria associated with small or mild doses of Adderall.

After more than 1 or 2 drinks, especially over a short time period, most people experience symptoms that can include:

  • stumbling, unsteady movement, or poor coordination
  • slurred speech
  • disorientation
  • reduced reaction time
  • reduced ability to think rationally
  • distorted judgment

Symptoms will depend on the person’s body weight, medical conditions, and history of alcohol usage.

If someone continues to drink alcohol, they will experience increasingly severe symptoms. Symptoms associated with heavy alcohol consumption include:

  • loss of control over body movement
  • inability to feel pain
  • inability to make rational decisions
  • total lack of judgment
  • vomiting
  • loss of consciousness

If someone misuses Adderall repeatedly, they can develop very unpleasant symptoms, even if they have a prescription for the medication.

Symptoms and side effects of repeated Adderall misuse include:

  • anger and aggression
  • paranoia
  • psychosis

When someone consumes too much Adderall, it can interfere with their body’s chemical signaling, causing serious, life-threatening symptoms.

People who think they may have taken too much Adderall should call the emergency services immediately, or ask someone to take them to the emergency department of a hospital.

If someone has the signs and symptoms of an Adderall overdose but is not able or willing to seek medical attention, someone else must call the emergency services for them or take them to the nearest hospital. Paramedics can give people medicine to return blood flow to their heart and reduce seizures.

Symptoms associated with using high doses of Adderall over the short-term include:

  • stomach cramps
  • dry mouth
  • difficulty sleeping
  • headaches and dizziness
  • changes in mood
  • restlessness or anxiousness
  • loss of appetite
  • nausea, vomiting, and diarrhea

Symptoms associated with long-term use of high doses of Adderall include:

  • irregular heartbeat
  • weight loss
  • very high body temperature
  • abnormally high or low blood pressure
  • chest pains
  • hallucinations
  • difficulty breathing
  • nerve issues that can cause seizures

Not much research has been done on the specific effects of mixing alcohol and Adderall. However, the studies that exist often show that combining the two drugs tends to greatly increase the risk of experiencing symptoms, such as:

  • heightened or lengthened period of euphoria while drinking
  • delayed onset of the sedating symptoms related to alcohol
  • altered perception of being drunk
  • intensified or exaggerated symptoms of Adderall or alcohol use


The greatest risk associated with drinking alcohol while taking Adderall is alcohol poisoning.

People who drink more alcohol than their livers can process may experience alcohol poisoning, where alcohol blood levels are so high they become life-threatening.

Symptoms of alcohol poisoning include:

  • uncontrollable vomiting, often when a person seems unconscious
  • coma
  • organ failure
  • death

As a prescription stimulant, Adderall itself is associated with quite a few risks, especially at high doses. Drinking may also intensify the effect Adderall has on the body.

Risks associated with very high doses or overdoses of Adderall include:

  • heart attack
  • seizures
  • heart and circulation failure
  • coma
  • death

The full extent of outcomes and effects linked with the combined use of Adderall and alcohol is not fully understood yet. However, some research has shown that the simultaneous use of alcohol and prescription stimulants is often linked with:

  • increased risk of substance abuse
  • greater likelihood of using illegal drugs or misusing other prescription drugs
  • lowered grade point averages
  • increased or prolonged symptoms of alcohol and stimulant use
  • decreased work or school performance
  • strained personal relationships
  • long-term lack of sleep

Addiction potential

Alcohol poisoning is the greatest risk associated with drinking alcohol while taking Adderall.

The U.S. Drug Enforcement Administration classifies Adderall as a Schedule II drug, meaning it carries a high risk of abuse and severe physical and psychological addiction.

The long-term use of Adderall can cause some people to develop a tolerance to the drug, meaning they need higher or more frequent doses to get the same effect.

Adderall misuse is also associated with a condition called substance use disorder (SUD), which can develop into addiction.

SUD can result in:

  • decreased or strained personal relationships
  • failure to keep up with the demands of work, school, and everyday life
  • reduced ability to cope with everyday stress

People with SUD also experience symptoms of withdrawal if they suddenly stop taking the drug or greatly reduce their dosage.

Symptoms of Adderall withdrawal include:

  • difficulty sleeping
  • unexplained sleepiness
  • depression


Although it is very dangerous to combine Adderall and alcohol, a lot of people who misuse Adderall consume alcohol at the same time.

Adderall can mask the effects of alcohol intoxication, making it much easier for individuals to consume too much alcohol. Studies have also shown that people who use Adderall for non-medical purposes while drinking alcohol are more likely to experience a wide array of adverse effects.

People who mix alcohol and Adderall also seem to be at an increased risk of developing substance abuse problems and are more likely to experiment with other prescription and illegal drugs.

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