We dose up on antioxidants as if they are the elixir of life. At best, they are probably ineffective. At worse, they may just send you to an early grave. For Linus Pauling, it all started to go wrong when he changed his breakfast routine. In 1964, at the age of 65, he started adding […]
A preliminary clinical trial shows that stem cell transplantation, along with a tolerable dose of chemotherapy, is safe and more effective at slowing down multiple sclerosis than other existing therapies. Scientists were able to slow down MS progression in a new clinical trial using stem cell transplantation. Multiple sclerosis (MS) is a chronic neurodegenerative condition […]
Integrase inhibitors give greater chance of viral suppression at delivery in pregnant women Jump to Raltegravir-based ART started in pregnancy Dolutegravir-based ART started in late pregnancy References Integrase inhibitor-based treatment with either raltegravir (Isentress) or dolutegravir (Tivicay, also in Triumeq) reduces viral load more rapidly than efavirenz if started in pregnancy, findings from two randomised […]
Older people who want to preserve their faculties may wish to consider rationing their TV time. A large new study of older adults found that those who spent at least 3.5 hours per day watching TV experienced a greater decline in verbal memory. The ‘passive activity’ of watching TV may impair memory in older people. […]
HIV-positive participant in vaccine study passes virus to sexual partner during treatment interruption An HIV-positive man transmitted HIV to his sexual partner after interrupting antiretroviral therapy as part of a research study into a therapeutic vaccine, French scientists reported in the Journal of Infectious Diseases last week. The case report underlines the importance of participants […]
A combination of MSD’s anti-PD-1 therapy Keytruda (pembrolizumab) and Pfizer’s tyrosine kinase inhibitor Inlyta (axitinib) has been found to reduce risk of death by nearly half compared to sunitinib as first-line treatment for advanced renal cell carcinoma (RCC). The results are taken from the pivotal Phase III KEYNOTE-426 trial, and show that the combination is […]
Craig Hendrix at HIVR4P 2018. Photo by Roger Pebody. Gus Cairns Published: 09 November 2018 Difference “equivalent to four days of PrEP per week rather than seven” A study presented at last month’s HIV Research for Prevention conference (HIVR4P) in Madrid shows that transgender women who are taking feminising hormones and also taking pre-exposure prophylaxis […]